- National Day of Prayer will be observed from 12:15-12:45 p.m. May 2 at Simpsonville United Methodist Church, 215 S.E. Main St.
- Eastminster Presbyterian Church, 2240 Woodruff Road, Simpsonville, will hold a special worship service on the National Day of Prayer at 6:30 p.m. May 2 in its outdoor worship area. In case of rain, the service will be inside.
- The Mauldin observance of the National Day of Prayer will be from noon-1 p.m. May 2 at Mauldin City Hall, 5 E. Butler Road. It will feature pastors from various denominations leading prayer, and a medley of patriotic songs. In case of rain, the event will be held in the Cultural Center, 101 E. Butler Road.
- The Fountain Inn observance of National Day of Prayer will start at 11:30 a.m. at City Hall, 200 N. Main St. The rain location is the banquet hall at the Center for the Visual and Performing Arts, 315 N. Main St.